Bortezomib is a relatively new drug for the treatment of multiple myeloma. Due to its slender therapeutic index, the drug is applied only by some healthcare professionals. Buying really should be under the route of an oncology expert who is well-versed in the usage of the drug.
Crucial: The drug information on this webpage is meant to get educational. It's not a substitute for clinical information. The data might not protect all doable takes advantage of, steps, interactions, or Negative effects of this drug, or safety measures being taken when applying it.
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erythromycin foundation will improve the stage or influence of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
black and tarry stools, crimson blood in stools, bloody vomit, or vomiting content that appears like espresso grounds
Convey to your well being treatment professional that you're making use of bortezomib in advance of owning any immunizations/vaccinations. Avoid connection with people who have just lately acquired Stay Dup 747 vaccines (like flu vaccine inhaled through the nose).
miconazole vaginal will boost the degree or impact of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unknown.
Use caution in hepatic impairment (lessen starting off dose); monitor hepatic enzymes in the course of treatment method Significant tumor load (hazard of tumor lysis syndrome); intently keep track of individuals with large tumor burden
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Hold all appointments together with your doctor as well as the laboratory. Your health care provider will buy particular lab checks to examine Your whole body's response to bortezomib.
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verapamil will increase the level or impact of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Bortezomib therapy requires a collaborative effort and hard work through the interprofessional Health care group. The drug could potentially cause hypotension, along with the nurse must Test the BP often. Nursing team ought to report any signs of adverse situations for the attending clinician right away and Look at Together with the pharmacist. If there are any Bortezomib questions about the drug, one particular should seek advice from While using the pharmacist very first.